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Benoist 2014, PMID 25187433, retracted 2025 per notice PMID 40312093) is potentiation of hepatocyte growth factor (HGF) signaling at the c-Met (MET) receptor, driving dendritic spine formation and synaptogenesis via PI3K-AKT

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doi: 10.1016/j.jfma.2012.02.022

These cells begin releasing HCG shortly after a fertilized egg implants into the lining of the uterus, usually about 610 days after ovulation