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Quality evaluation of the included studies The results of the risk of bias assessment are presented in Fig 3

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Symptom Details Capture the nature of pain (sharp, dull, burning), frequency, severity on a 0 to 10 scale, duration, and associated symptoms like stiffness, weakness, or radiating pain

The relative intensities of the excitation peaks depend on the redox state of the two cysteine residues engineered to be present on the surface of the roGFP2 barrel

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