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How Does 5-Amino-1MQ Work

Synthetic B12 allows medical professionals to efficiently supplement in people with a deficiency, a difficulty absorbing B12 through food, or with underlying conditions that impact B12 absorption

Form: Capsules (for research use only) Target: Nicotinamide N-methyltransferase (NNMT) inhibitor Suggested Application: Preclinical or in vitro metabolic studies Storage: Preserve in a cool, dry environment away from direct light 1

Sequence: YLRIVQCRSVEGSCGF

However, this remains a preclinical finding that has not been confirmed in human pharmacokinetic studies

It was confirmed by dual luciferase reporter assay that miR-29b-3p and miR-378g directly target the 3UTR of NNMT and negatively regulate NNMT expression