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The pathological association between nutrition and OA Obesity and OA: intertwined pathways of inflammation, mechanics, and diet Obesity is a critical risk factor for OA, driven by a synergy of mechanical overload and adipose tissue-mediated systemic inflammation

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38,39 Key active compounds in CB include oleanolic acid, ergosterol, and ursolic acid, and they exhibit activity against HCC by enhancing apoptosis, preventing tumor invasion, and regulating the proliferation of cancer stem cells and tumor cells

Both authors wrote, read, approved the study for publication, and provided their critical feedback and approved the final manuscript

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