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Dysfunction of the systemic or local dopaminergic system during inflammation has been found in animal models and patients with various inflammatory diseases, such as Parkinson disease, inflammatory bowel disease, rheumatoid arthritis, systemic lupus erythematosus, and multiple sclerosis, indicating an important role that DRs play in inflammatory diseases

The level of BCL-2 protein may thus serve as an additional marker of senescence

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Mitochondrial GSTs are known as the kappa class in mammals and are mostly found in the mitochondrial matrix [60] and peroxisomes [61]

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They do not replace them