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M., Moharil, R

Studies from the Linton group indicated that the feedback associated with upregulated COX-2 expression in macrophages due to COX-1 deficiency might be the major cause of atherosclerosis

Clemente MG, De Virgiliis S, Kang JS et al (2003) Early effects of gliadin on enterocyte intracellular signalling involved in intestinal barrier function

[66] Moderate alcohol consumption 3060 minutes before sleep, although decreasing, disrupts sleep architecture

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Together with the observation that CNS myelin appears to be a major target, this spurred development of various animal models, with the experimental autoimmune encephalomyelitis (EAE) mouse model being the most popular (Baxter, 2007)