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Antioxid Redox Signal 28(6):445462

Kynurenine pathway metabolites: relevant to vitamin B-6 deficiency and beyond

McCann H, Cartwright H, Halliday GM

(PubMed) Coles BF, Kadlubar FF

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CYP3A4 induction also leads to consequent generation of acetaldehyde and lipid peroxidation-derived protein-aldehyde adducts in the liver (Niemel et al., 2000), which are hybrid compounds resulting by interaction of alcohol metabolites with other complex molecules, confirming previous findings in the liver of alcohol-treated rats (Niemel et al., 1998)