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Tumor progression was followed using in vivo bioluminescence imaging as this technology allows for the detection of tumor burden in a sensitive and noninvasive manner

RESULTS: 1) After 48 hour exposure to 5 mM and 20 mM glucose, insulin secretion in response to 20 mM glucose were 134.4+/-16.8 fmol/10 islets/hr and 90.0+/-10.2 fmol/10 islets/hr, respectively