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Diet is a primary determinant of gut microbiota composition, which subsequently modulates inflammatory pathways in chronic diseases

GPX4 specifically catalyzes the oxidative activity of lipid peroxides in a glutathione-dependent manner, thus protecting cells from the threat of ferroptosis [12, 17, 18]

Therefore, we performed our mitochondrial analyses upon 20 h of starvation to ensure sufficient nutrient stress in the absence of a loss of cell viability

Possible implications: Together, the novel findings in this study may have various important implications on muscle physiology and pathology and call for continuation studies on diverse physiological, pathological and therapeutic topics

Protein expression levels of PPAR, C/EBP, ACC, and FASN were also markedly reduced in differentiated Ssu72 knockdown 3T3-L1 cells (Fig

PMID: 121 BallaATranBValtariAStevenPScarpelliniCAugustynsKet al