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Kumagai E, Hosohata K, Furumachi K, et al

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Furthermore, MASLD is independently associated with increased risks of cardiovascular disease, chronic kidney disease, and various extrahepatic malignancies, posing a substantial threat to public health

10.1016/j.chc.2019.08.008 22 JiangT.ZhangY.BaiM.LiP.WangW.ChenM.et al (2019)

Estas sustancias actan como detergentes produciendo un dao inespecfico de la pared celular con necrosis de adipocitos y posterior infiltrado inflamatorio con predominio de neutrfilos y posteriormente de linfocitos T, granulomas y clulas espumosas4

In particular, the review focuses on summarizing how the increase of gut microbial metabolite TMAO affects CVDs including atherosclerosis, heart failure, hypertension, arrhythmia, coronary artery disease, and other CVD-related diseases