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A typical FDA-approved regimen for pernicious anemia includes: 100 g IM/SC daily for 67 days Then every other day for 7 doses Then every 34 days for 23 weeks Followed by 100 g monthly for life Schedule follow-up and monitor progress Potassium levels should be monitored during the first 48 hours of treatment, as rapid red blood cell production may lead to hypokalemia and, rarely, sudden death

Toradol may be used for pain-related support, and Zofran may be used for nausea-related support when appropriate after review by licensed medical professionals

In the United States, cyanocobalamin injection is an FDA-approved drug for the treatment of B12 deficiency, including pernicious anemia