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In this Review, we focus on advances in our understanding of inhibition of the HGF/c-MET pathway in patients with gastro-intestinal cancers, the prominent challenges facing the clinical translation and implementation of agents targeting HGF/c-MET, and discuss the various efforts, and associated obstacles to the discovery and validation of biomarkers that will enable patient stratification in this context

Some protocols use two-week escalation intervals with higher starting doses

BPC-157 (Body Protection Compound-157) is a 15-amino-acid synthetic peptide gaining popularity for its supposed he aling benefits from repairing gut lining to accelerating muscle and tendon recovery

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The 10 mg dose achieved 21.4%, and even the 5 mg dose delivered 16.0%