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Safety remains a major concern, particularly with respect to long-term exposure, immunogenicity, and the accumulation of nanomaterials in the brain or peripheral organs (Wu et al., 2023)

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doi: 10.1089/thy.2021.0662 [DOI] [PubMed] [Google Scholar] 12.Husson O, Haak HR, Oranje WA, Mols F, Reemst PH, van de Poll-Franse LV