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A study where small molecule, REV-ERB agonists like SR9011 and SR9009 and were used showed that they could repress certain processes like metabolism, cell proliferation, and inflammation that are required for tumorigenesis (Scheiermann et al., 2013)

Targeting T cell metabolism in the treatment of liver cancer Competition between tumor cells and TILs for glucose uptake can lead to glucose deficiency in the TME and lactate accumulation

Cell Tissue Res 400 , 1734 (2025)

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