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For Vitamin B12, levels below 200 pg per mL indicate deficiency

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In summary, despite many studies indicating the oral administration of vitamin B12 to be easy, effective and less costly than intramuscular administration, their designs, and in some cases their methodological limitations, mean that debate still surrounds the effectiveness of the oral route

Methionine, in the form of S-adenosylmethionine (SAM), is required for many methylation reactions, including DNA methylation

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