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The pore size of the tunnel is determined by the steric obstruction generated by three hydrophobic residues, Ile201, Val205, and Leu214 [136]

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[43] [44] Reaction of dihydrolipoyl dehydrogenase In the reaction sequence catalyzed by the pyruvate dehydrogenase complex, dihydrolipoyl dehydrogenase catalyzes the fourth and fifth steps

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