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ZFAS1 has been shown to enhance the interaction between the key kinase AMPK and the major regulator of EMT, ZEB1

Furthermore, although an alum-adjuvanted double-inactivated SARS-CoV vaccine elicited higher antibody titres in aged mice, it skewed the IgG subclass toward IgG1 instead of IgG2, which was associated with a T helper 2 (T H 2)-type immune response, enhanced eosinophilia and lung pathology 13

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