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Our metabolomics analysis profiling almost 300 metabolites from 56 patients and 19 controls provides a roadmap for understanding the role of neutrophil metabolism in severe COVID-19, in which neutrophil dysregulation is a major pathogenic mechanism

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doi: 10.1038/nrc3366 82 YeW

However, the reaction was not sensitive to the concentrations of NH 4 OH or IACN, as varying these concentrations using 15 L NH 4 OH and 510 L IACN did not affect the yield determined by HILIC LC-MS (data not shown)

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