glutathione s transferase alverine transferases: substrates, inihibitors and pro-drugs in cancer and neurodegenerative diseases The Multifaceted Role of Glutathione

Oxidation of the Cys residue in the active site of PTPs by ROS abrogates its nucleophilic properties, thereby inhibiting PTP activity (87)

Maiorino M, Scapin M, Ursini F, Biasolo M, Bosello V, Floh L (2003) Distinct promoters determine alternative transcription of gpx-4 into phospholipid-hydroperoxide glutathione peroxidase variants

These findings confirmed that MLE has the potential to protect liver from APAP-induced inflammation, and the protecting mechanism might involve decreasing oxidative stress and regulating the innate immunity involving MyD88

Further investigation is warranted to adapt and optimize these strategies for effective and safe nanozyme-based therapy in IMIDs

Glymphatic system dysfunction: a novel mediator of sleep disorders and headaches

The differences between two groups were assessed by two-tailed and unpaired t tests