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Targeting mitochondrial dynamics and metabolic flux regulation offers a novel strategy to disrupt cancer cell metabolic plasticity and enhance therapeutic efficacy [46]

Stress Reporter Assay of AQ-QI and DEAQ-QI To identify the stress response pathways upon AQ-QI and DEAQ-QI exposure, oxidative stress response (SRXN1-GFP), ER stress response (CHOP-GFP), inflammation response (ICAM1-GFP), and DNA damage response (p21-GFP) pathways were measured with a high-content image-based BAC-GFP stress responses reporter assay (Wink et al., 2014, 2017)

The efficacy of the PET probe has been demonstrated in rodents, which showed GluN2B-NMDA receptor expression in the cortex, striatum, thalamus, and hippocampus [111]

Front Pharmacol 13:868365 Shaaban AA, Zaghloul RA, Kafl HE, El-Kashef DH (2023) Ameliorative effect of desloratadine against cisplatin-induced renal and testicular toxicity in rats: attention to TLR4/NLRP3 inflammasome signaling pathway

Galactose, a metabolite regulating oxidative phosphorylation, was also higher in the astrocytic murine model

Blood test markers to discuss with a clinician Marker CBC with differential Why it matters Screens broad blood-cell patterns that may affect fatigue, infection context, or general health interpretation