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Cyanocobalamin is the most widely characterised and stable form of injectable B12

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171,172 In an older randomized placebo-controlled trial in 45 women with fibromyalgia and low levels of IGF-1 (a peptide made in the liver in response to stimulation by growth hormone), those receiving subcutaneous growth hormone injections for nine months had greater reductions in tender points and fibromyalgia impact scores and were more likely to experience global improvement compared with those receiving placebo

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Additionally, Cbl deficiency has been associated with decreased immune function, such as reduced CD8 T cells and natural killer cells [29]

Furthermore, a large study of 201 Mortons neuroma sufferers found that the threshold for steroid injection failure was 6.3 mm, the study demonstrated neuromas with a size larger than 6.3 mm can be suspected to require further treatment with a certainty of 84%. (15)