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Results The Generation and Verification of VLP-Conjugated CspZ Proteins We re-evaluated the potential of CspZ as a vaccine by utilizing two different strategies: conjugating CspZ with VLP (VLP-CspZ) and further modifying CspZ to eliminate its FH-binding activity (VLP-CspZ-Y207A/Y211A)

We confirm that all three chemotypes, as well as genetic loss of GPX4 26 , share a pattern of cell killing across a range of cancer cell lines (Figure 7B)

doi:10.1038/35012083 Seifert G, Steinhauser C (2001) Ionotropic glutamate receptors in astrocytes

Referring to the collected information on the clinicopathological features of patients suffering from papillary thyroid carcinoma, a qRT-PCR analysis was conducted on clinical samples to evaluate whether differences existed in the expression of FTO and SLC7A11 in tumor tissues and corresponding non-tumor normal tissues

The reduced vascular branching and density suggest effective suppression of tumor-induced neovascularization, a key hallmark of aggressive tumor progression

EuB reviewed and contributed to the writing of the manuscript