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There is a huge amount of evidence implicating inflammation in atherosclerosis and acute coronary syndromes (ACS) and a variety of circulating markers of inflammation have been examined for their ability to predict either the presence of vascular disease or the risk of vascular events in a broad range of clinical settings.7 These markers included CRP, serum amyloid A, fibrinogen, neopterin, lipoprotein-associated phospholipase A2, soluble CD40 ligand, heat shock proteins, matrix metalloproteinases, myeloperoxidase, pro-inflammatory cytokines and many circulating adhesion molecules.6 The identification of vulnerable plaques in vulnerable patients using imaging techniques or inflammatory biomarkers is one of the most promising areas of research in modern cardiology and could revolutionise cardiovascular practice