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Disclosures: Priyata Dutta: Nothing to Disclose, Robert Fontana: kezar pharmaceuticals: Grant/Research Support, Takeda Pharmaceuticals: Grant/Research Support, Nikhilesh Mazumder: Nothing to Disclose 1361 THE PATIENT AND KIDNEY GRAFT OUTCOMES OF SAFETY NET KIDNEY TRANSPLANTS ARE SIMILAR TO KIDNEY TRANSPLANT RECIPIENTS WITHOUT A PREVIOUS LIVER TRANSPLANT: A RETROSPECTIVE UNOS DATABASE ANALYSIS Mohanad Awadalla 1 Yong-Fang Kuo 2 Ashwani Singal 3 , 1 Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, 2 UTMB Galveston, 3 University of Louisville Background: The Organ Procurement and Transplantation Network (OPTN) implemented the allocation policy in 2017 to standardize the approach to simultaneous liver-kidney (SLK) listing and optimize the use of deceased donor kidneys

Results: Log- rank analysis revealed a significantly higher rate of harmful relapse (p = .021) and a trend towards higher any relapse rates (p = .094) in patients transplanted for ARLD + AH compared to those with ARLD alone

Acknowledgements We would like to thank the members of the Park laboratory, the UCLA Molecular Instrumentation Center, the UCLA Metabolomics Center and the UCLA Proteome Research Center, as well as M

injections (between 15:00 and 17:00) of 100 nmol kg 1 MK-801, 10 nmol kg 1 semaglutide, 100 nmol kg 1 GLP-1MK-801 or vehicle, with concomitant measurements of body weight and food intake