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The only active comparator ever used against cagrilintide monotherapy was liraglutide 3.0 mg in a Phase 2 study not tirzepatide so every ranking of the two is cross-trial inference across different populations and endpoints

10.1016/j.npep.2007.11.002 40 Fruitier-ArnaudinI.CohenM.BordenaveS.SannierF.PiotJ.-M

Some are clinically validated with thousands of patients in the evidence base