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It contains diosgenin, a plant compound used in the laboratory to synthesize hormones like progesterone, which is why its often included in hormone-support formulas

Transl Lung Cancer Res (2014) 3:4035

The lowered threshold to pain is caused by abnormalities of CNS processing of sensory stimuli by the brain, and is not caused by any primary muscle or soft-tissue dysfunction

A big reason for these changes is the natural decline of certain compounds that our bodies produce in abundance when we're young

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212 ShenL.LiuL.JiH.-F