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As the first relay stations for auditory information entering the central nervous system, brainstem structures like the CN are among the first to undergo neural plasticity

1998 Apr;42(4):485-92

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Symptoms of Goat Polio Off feed/water Disorientation Staggering Circling Stargazing Convulsions Involuntary eye movements Temporary blindness Sudden death Note: Stargazing is characterized by the goats head thrown backwards due to rigid neck muscles

Furthermore, melatonin inhibits the activation of nuclear factor kappa B (NF-B) as a key transcription factor that mediates the inflammatory response [81]