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J Dtsch Dermatol Ges 2017

Snezhkina AV, Kudryavtseva AV, Kardymon OL, Savvateeva MV, Melnikova NV, Krasnov GS, et al

Anegbe, B., Ifijen, I

88 However, itraconazole was shown to inhibit the development of GBM through an autophagic signaling induction, whereas the blockage of autophagy significantly reverses the antiproliferative effects of this molecule, suggesting an antitumor role of autophagy in response to itraconazole

(Procedure adapted from Shang et al JACS V138 pp 10132-10135 (2016))

Recent single-cell profiling has identified multiple TEC phenotypes, including tip-like TECs, which are characterized by high migratory and angiogenic activity and correlate with poor clinical outcomes across various cancer types [134, 135]