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Although these interventions have shown remarkable efficacy in preclinical models, extensive studies are still required to validate their safety, efficacy and controllability in complex physiological settings and to further optimize targeted delivery systems to facilitate clinical translation

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Renal toxicity associated with disease-modifying antirheumatic drugs used for the treatment of rheumatoid arthritis

Gi gc l: 295.000.Gi hin ti l: 280.000

Furthermore, kaempferol decreased the expression of anti-apoptotic proteins such as Bcl-xL and Bid, while upregulating pro-apoptotic proteins like Bad and Bik