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8.2.2 Mass Spectrometry (MS) Fragmentation Characteristics Mass spectrometry is the most accurate method for identifying SAG

A placebo-controlled trial in 252 patients with major depressive disorder who were randomized to 12-weeks NAC or placebo added to standard antidepressant treatment, and followed up to 16 weeks, found no significant differences in depressive symptoms assessed using the Montgomery-sberg Depression Rating Scale (MADRS) between the two groups at week 12 (primary endpoint) [144]

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Funding The author(s) declare that no financial support was received for the research and/or publication of this article