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PMID: 41751402 J Biol Chem SLC25A3 negatively regulates NLRP3 inflammasome activation by restricting the function of NLRP3

Pre-treatment of islets isolated from Slc7a11 -KO mice and control mice with the GSH precursor -glutamyl-cysteine (GGC) removed the previously observed difference between the groups

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Similarly, chronic exposure of Hcy for 36 days also elevated striatal Hcy concentrations in mouse brains and decreases dopamine turnover, reduced tyrosine hydroxylase immunoreactivity in the substantia nigra, accompanied by marked reductions in locomotor performance [172]

[DOI] [PubMed] [Google Scholar] 331.Kops G