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According to the amyloid cascade hypothesis, the initial event in AD is the misfolding and aggregation of A, which triggers a series of pathological changes, including abnormal tau phosphorylation, neuroinflammation, vascular abnormalities, and neurodegeneration (59)

GD contributed to the evaluation of the strains obtained in the different types of

Synaptic degeneration in Alzheimer disease

In this study, although SNRPD1 was not enriched in any specific pathway, the increase in SNRPD1 expression suggests potential risks related to tumor proliferation that deserve future monitoring during APP treatment

E., Peiris-Pages, M., Pestell, R

Ho DJ, Calingasan NY, Wille E, Dumont M, Beal MF