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Given the wide role of GSTs in drug metabolism, including the resistance of some tumors to chemotherapeutic agents, the significant inter-individual variations in GST expression including the association of null phenotypes with cancer incidence, and the influence of diet and other factors on GST expression, these research tools can benefit many fields

Crosstalk between apoptosis, necrosis and autophagy

Biofactors 9 , 141148 (1999)

it's a biochemical alarm signaling deeper genetic and metabolic breakdowns that drive inflammation, oxidative stress, and serious health risks

Nat Cell Biol 14: 829837 Wang JB, Erickson JW, Fuji R, Ramachandran S, Gao P, Dinavahi R, Wilson KF, Ambrosio AL, Dias SM, Dang CV, Cerione RA (2010) Targeting mitochondrial glutaminase activity inhibits oncogenic transformation