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Additional relevant literature was identified through cross-referencing

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Limosilactobacillus reuteri FN041 induced effect on the intestinal TJ barrier was accompanied by the inhibition of HFD-induced increase production in LPS, TNF- and IL-16

4 Molecular mechanisms of the activation of pro-inflammatory response caused by bacterial invasion Dysbacteriosis of the gut microbiota can lead to disruption of intestinal barrier function and immune homeostasis

These are drugs used to treat type 2 diabetes, as well as drugs used to treat obesity