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In contrast to the exacerbating effect of COX-1 ablation on NASH, supplementation with COX-1 inhibitors, such as genistein and SC-560, appears to offer protection against diet-induced NAFLD and improve glucose tolerance in mice

Sixty-eight pregnant women in Bangladesh received 250 mcg oral vitamin B 12 or placebo once daily beginning during their first trimester of pregnancy and continuing until 3 months postpartum