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Oral Melanotic Macule: Symptoms and Treatment Skinsight Melanotic macule. Benign. Dark spot on labia (or lip). Analogous to lentigo simplex. Hyperpigmented basal keratinocytes & dermal melanophages. Slight in single basal melanocytes; NO nests. More info like this in Oral Melanotic Macule: a small dark spot in the mouth ArtSmiles Freckle on Lip: Meaning, Causes and Is It Dangerous? (Labial Melanotic Macule) Summit Enlighten Laser to treat labial melanotic macules on the lip before and after. Facebook Oral Melanotic Macule MEDizzy

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