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doi: 10.1016/j.bbrc.2018.08.069 39 WhiteMALinCRajapaksheKDongJShiYTsoukoEet al

Conclusions Our study demonstrates that pharmacological Vit-C effectively induces cytotoxicity in both non-aggressive (MCF-7) and aggressive (MDA-MB-213) forms of BC tumor spheroids at various concentrations

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Androgens signal by binding to the androgen receptor (AR), which interacts with androgen response elements (AREs) and recruits co-activators and co-repressors to regulate transcription of AR target genes