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Los efectos gastrointestinales son los ms comunes , incluyendo nuseas (12-22% de pacientes), diarrea (12-16%), vmitos (5-9%), estreimiento (6-7%) y dolor abdominal

doi: 10.1016/j.jncc.2025.01.007 Summary Keywords colorectal cancer, microsatellite stable, antibody-drug conjugate, immunoconjugate, immuno-oncology Citation Wang Y, Lu K, Xu Y, Xu S, Chu H and Fang X (2025) Antibody-drug conjugates as immuno-oncology agents in colorectal cancer: targets, payloads, and therapeutic synergies

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In recent years, more and more researchers have paid attention to the emerging role of the cyclic GMP-AMP synthase (cGAS) stimulator of the interferon genes (STING) pathway

Neurons, with their high metabolic rate and GPX4-dependence, are the primary targets ( Adding a crucial temporal dimension, the contribution of ferroptosis evolves dynamically post-stroke

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