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PubMed, Engevik, Melinda A., et al

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The oxidative nature of FB 1 mediates acute lipid metabolism

It was shown that the deletion of E155 in GSTO1-1 has a significant effect on enzymatic stability and may consequently alter the physiologic role of the enzyme in the brain regions 53

Moreover, Zhang et al

Similarly, peroxisome proliferator-activated receptor (PPAR)- agonists such as fenofibrate promote fatty acid oxidation, which may help clear the lipid accumulation associated with mitochondrial dysfunction and reduce inflammation-driven atherosclerosis (159)