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However, we are substituting the term plan of treatment for plan of care in the regulation to be consistent with the other uses of plan of treatment found at 424.24(c)

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As we stated in the proposed rule, we believe the AMA's approach may possibly mitigate nonresponse bias, which created challenges using previous PPIS data

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Additionally, they were able to show that activation of mast cells in osteoarthritis is through IgE/FcRI

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