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Conventional chemical pesticides play a critical role in controlling plant diseases, thereby ensuring crop yield and food security [2, 3]

Purine pathway The purine metabolites HX and XAN and the ratio XAN/XANTH were decreased significantly, while the ratios PXAN/XAN and URIC/XAN were elevated at 8 weeks compared with baseline, indicating a similar decline in the canonical pathway of purine metabolism, as observed in the tryptophan and tyrosine pathways

The GSH:GSSG ratio is a widely used biomarker of cellular oxidative stress, with depletion implicated in neurodegeneration, hepatic injury, and immune dysfunction

Identification of metabolites reproducibly associated with Parkinsons Disease via meta-analysis and computational modelling

Only a small percentage of a standard oral dose is absorbed through this active pathway, and that number drops further when digestion is impaired

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