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doi: 10.1007/s12640-023-00674-z 32 BoetsEGomandSVDerooverLPrestonTVermeulenKDe PreterVet al

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For example, curcumin has been evaluated in Phase II clinical studies in pancreatic cancer and colorectal cancer patients, where oral doses up to 8 g/day demonstrated acceptable safety but limited systemic exposure, highlighting pharmacokinetic challenges

Mechanism: psychedelic-derived, targeting the 5-HT2A receptor (a serotonin receptor that changes how brain networks talk to each other)

Cell growth is regulated by the patched/hedgehog intracellular signaling system, and continuous activation of this pathway results in the formation of BCC

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