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Main text Vitamins Vitamin A and Carotenoids Vitamin A is a group of animal-derived fat-soluble retinoids essential for cell growth, cell differentiation, immunity, and vision

It is naturally produced in the body from three amino acids named glycine, proline, and hydroxyproline

Hypoxia stabilizes HIF-1, enabling its nuclear translocation and activation of hypoxia-responsive genes, including those involved in autophagy

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In experimental systems, this dual approach provides a more representative model of coordinated growth hormone regulation compared to isolated receptor activation