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Given that the intestinal epithelial barrier function was found to be positively regulated by activation of the intestinal cannabinoid type 1 receptor (CB1R) 27 , we treated mice with ACEA (arachidonyl-2-chloroethylamide), a selective CB1R agonist 28 during the autoimmune noninflammatory pre-phase of CIA from day 17 to day 27 after immunization

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Similar content being viewed by others Introduction Protein splicing is a post-translational process by which an intervening polypeptide, called an intein, catalyzes its own excision from the flanking polypeptides, or exteins, as well as ligation of the exteins (Figure 1A)

In addition to their origin, these compounds can also be classified functionally, based on their redox properties, solubility (water-soluble or fat-soluble) and their ability to interact with different cellular compartments [16] (Table 1)