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The neurohormone melatonin, primarily secreted by the pineal gland, has gained recognition as a promising therapeutic agent due to its antioxidant, anti-inflammatory, and neuroprotective effects

The study by Liu et al (106) also revealed a decline in cytochrome c release from mitochondria into the cytoplasm and a decrease in intra-mitochondrial JC-1 monomers, which protected mitochondrial function, thus improving survival and cardiac function in mice

The researchers said that future research may look at any role that ergothioneine and glutathione have in decreasing the likelihood of neurodegenerative diseases, such as Parkinsons disease and Alzheimers disease

In contrast, vitamin C supplementation does not appear to increase levels in the brain at all (Terpstra et al., 2011)

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142 In the most severe cases, the marked elevation of body temperature initiates a series of interrelated effects that can differ in their relative prominence in different cases