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Biomedicines 2025;13:733 342

Advanced glycation end-products in diabetic nephropathy

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It has been reported that MKK3 and MKK6 are key upstream kinases regulating the phosphorylation and activation of p38 (36)

While disruption of transport of lactate into cancerous cells (i.e., reducing lactate shuttling into cancerous cells) is considered beneficial, upregulation in neuropathological cases shows merit for research