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The protein network was created with default parameters except for the confidence score being set to 0.7 to investigate only high-confidence interactions

The mutant shows increased thermolability compared to wild-type V457Y/E597D site-directed mutagenesis V47R - isoform PTPalpha, mutation turns alpha isoform to PTP1B-like enzyme in substrate recognition W179F site-directed mutagenesis, the mutation in PTP1B causes only a minor reduction in kcat of about 2fold at pH 5.5, and the pH-rate profile remains fully bell-shaped

pylori infection may change the expression of miRNAs in oxidative stress, interfering with the methylation of miRNAs, which may contribute to the mechanism triggering the onset of gastric carcinogenesis

Also Referenced As PL14736 Body Protection Compound 157 Gastric Pentadecapeptide BPC 157 Pentadecapeptide BPC 157 Sourced through an established North American supply partner that conducts onsite manufacturer reviews against documented cGMP practices and applicable ISO quality criteria

PLOS ONE 5 , e12931 (2010)

H&E (G1003), Alcian blue (G1027), and Prussian blue staining kit (G1029) were provided by Servicebio