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Rights and permissions About this article Cite this article Hargreaves, I.P., Sheena, Y., Land, J.M

Experimental research in rat aortic endothelial cells showed that capsaicin-induced TRPV1 activation elevates NO levels by up to 29%, alongside increased levels of the essential cofactor BH4 and cGMP, which are critical for eNOS function and downstream signaling, respectively