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These findings indicate that the antidepressant effects of CBD are sex-dependent, highlighting the modulation of hippocampal neuroinflammatory and estrogenic pathways in males ( CBD also induced a potential antidepressant effect in the chronic stress model in male rats

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Beneficial effects of Lepidium meyenii (Maca) on psychological symptoms and measures of sexual dysfunction in postmenopausal women are not related to estrogen or androgen content