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doi: 10.1021/acsnano.3c11832

Research provided evidence that the hypoxic stress in glioma and GBM cells increases protein catabolism (142,143)

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10.1016/j.neuint.2008.01.009 18 BakavayevS.ChetritN.ZvagelskyT.MansourR.VyazmenskyM.BarakZ.et al

Scienceasia49 (2023): 177-183

Similar observations were noted in later human studies [56, 57], with the peak serum TMAO observed within hours following oral administration of the tracer [56]